Article No
AC-0127RUO
Application | IHC |
Article No | AC-0127RUO |
Country Availability | SE, FI, DK, NO, IS, FO, GL |
Clone | EP130 |
Clone Type | monoclonal |
Conjugation | Unconjugated |
Description | Somatostatin for Research Use Only |
Supplier | Cell Marque (Epitomics) |
Format | Concentrate |
Notes | Somatostatin is a peptide hormone that regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G-protein-coupled somatostatin receptors and inhibition of the release of numerous secondary hormones. This hormone has two active forms produced by alternative cleavage of a single preproprotein: somatostatin-14, composed of 14 amino acids and somatostatin-28, a prohormone composed of 28 residues. Somatostatin is secreted by D-cells of the islets of Langerhans in pancreas, endocrine cells of the gastrointestinal tract, bronchopulmonary system, thymus, and C cells of the thyroid. Somatostatin positive cells may also be present in medullary thyroid carcinomas, C cell hyperplasia, thymic tumors and pulmonary small cell carcinomas. An antibody to Somatostatin can be used to identify pancreatic islet cell hyperplasia as well as islet cell tumors, such as somatostatinomas. |
Product Type | Antibodies Primary |
Protocol | IHC: 1:100-200 |
Research area | Metabolism, Neuroscience |
Size | 0.1 mL |
Source / Host | rabbit |
Species Reactivity | human |
Storage | Store at 2-8 °C. Don’t use after expiration date provided on the vial. The users must validate any storage conditions other than those specified. |
Product Page Updated | 2023-10-02T09:48:37.458Z |