Article No
AFC-ZLO4P9-0.1
Anti-Hu CD264 Purified Azide Free
Anti-Hu CD264 Purified Azide Free
Antibodies Primary
Specifications
| Application | FC |
| Article No | AFC-ZLO4P9-0.1 |
| Biosite Brand | Biosite Flow |
| Country Availability | all |
| Clone | TRAIL-R4-01 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | Anti-Hu CD264 Purified Azide Free |
| Supplier | Nordic Biosite |
| Entrez Gene ID | 8793 |
| Format | Purified Azide Free |
| Immunogen | TRAIL-R4 (aa 1-210) - hIgGhc fusion protein |
| Isotype | IgG1 |
| Keywords | Apoptosis (Human), CD and Related Antigens (Human), Apoptosis |
| Notes | TRAIL-R4 (CD264, TR4, DcR2, TRUNDD), expressed mainly on CD8+ and NK cells, belongs to receptors of TRAIL, a TNF-like membrane toxic protein that induces apoptosis in many tumour cells, but not in normal cells. TRAIL-R4, however, contains partially truncated death domain, thus it is unable to induce apoptosis and serves as a negative regulator of apoptotic signaling by impairment death-inducing signaling complex (DISC) processing. TRAIL-R4 interacts with death receptor 5 (DR5) in the native DISC in a TRAIL-dependent manner and prevents its corecruitment with death receptor 4 (DR4). |
| Alias Names | TNFRSF10D, DcR2, TRUNDD, TRAILR4 |
| Previous Article No | AFC-4105-2, AFC-ZLO4P9-0.1 |
| Product Type | Antibodies Primary |
| Protocol | Flow cytometry: Recommended dilution: 1-4 μg/ml. |
| Purification | Purified by protein-A affinity chromatography. |
| Purity | > 95% (by SDS-PAGE) |
| Research area | Cell Death |
| Size | 0.1 mg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | Store at 2-8°C. Do not freeze. |
| Substrate / Buffer | Phosphate buffered saline (PBS), pH 7.4 |
| Technical Specifications | The antibody TRAIL-R4-01 reacts with an extracellular epitope of TRAIL-R4, a 42 kDa transmembrane protein expressed on various blood cells. |
| UniProt Number | Q9UBN6 |
| Product Page Updated | 2024-01-03T12:18:20.318Z |
