Article No
AFC-PECVPC-0.1
Anti-Hu CD300e Purified
Anti-Hu CD300e Purified
Antibodies Primary
Specifications
| Application | FC, IP, WB |
| Article No | AFC-PECVPC-0.1 |
| Biosite Brand | Biosite Flow |
| Country Availability | all |
| Clone | UP-H2 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | Anti-Hu CD300e Purified |
| Supplier | Nordic Biosite |
| Entrez Gene ID | 342510 |
| Format | Purified |
| Immunogen | CD300e-HA-transfected cells |
| Isotype | IgG1 k |
| Keywords | CD and Related Antigens (Human) |
| Notes | CD300e / IREM-2 (immune receptor expressed by myeloid cells 2), also known as CLM2 or LMIR6, is a monomeric transmembrane glycoprotein with a single extracellular immunoglobulin-like domain. Intracellularly it associates with DAP-12, an ITAM-containing adaptor molecule. CD300e is expressed on mature monocytes and peripheral blood myeloid dendritic cells. Its crosslinking leads to release of pro-inflammatory cytokines, and increased expression of activation markers. |
| Alias Names | CLM2, CMRF35-A5, LMIR6, IREM-2, PlgR2 |
| Previous Article No | AFC-4569-2, AFC-PECVPC-0.1 |
| Product Type | Antibodies Primary |
| Protocol | Flow cytometry: Recommended dilution: 1-4 μg/ml. |
| Purification | Purified by protein-A affinity chromatography. |
| Purity | > 95% (by SDS-PAGE) |
| Research area | Immunology |
| Size | 0.1 mg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | Store at 2-8°C. Do not freeze. |
| Substrate / Buffer | Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Technical Specifications | The mouse monoclonal antibody UP-H2 recognizes an extracellular epitope on CD300e / IREM-2, a 32 kDa glycoprotein expressed by mature monocytes and peripheral blood myeloid dendritic cells. |
| UniProt Number | Q496F6 |
| Product Page Updated | 2024-01-03T12:18:20.318Z |
