Article No
AFC-TMN89G-100
Specifications
| Application | FC |
| Article No | AFC-TMN89G-100 |
| Biosite Brand | Biosite Flow |
| Country Availability | all |
| Clone | M38 |
| Clone Type | monoclonal |
| Conjugation | APC |
| Description | Anti-Hu CD81 APC |
| Recommended Dilution | The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary. |
| Supplier | Nordic Biosite |
| Entrez Gene ID | 975 |
| Format | APC |
| Immunogen | MOLT-4 (human T-ALL cell line) |
| Isotype | IgG1 |
| Keywords | CD Antigens & MHC (Veterinary), CD and Related Antigens (Human) |
| Notes | CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells, e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus. |
| Alias Names | S5.7, CVID6, TAPA1, TSPAN28 |
| Previous Article No | AFC-4762-2 |
| Product Type | Antibodies Primary |
| Protocol | Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. |
| Purification | Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography. |
| Research area | Immunology |
| Size | 100 tests |
| Source / Host | mouse |
| Species Reactivity | rabbit, cat/feline, human |
| Storage | Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze. |
| Substrate / Buffer | Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Technical Specifications | The antibody M38 reacts with an extracellular epitope of CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells. |
| UniProt Number | P60033 |
| Product Page Updated | 2024-01-03T12:18:20.318Z |
