Article No
AFC-RUQ7BR-0.1
Specifications
| Application | FC |
| Article No | AFC-RUQ7BR-0.1 |
| Biosite Brand | Biosite Flow |
| Country Availability | all |
| Clone | 4B12 |
| Clone Type | monoclonal |
| Concentration | 0.5 mg/ml |
| Conjugation | PE |
| Description | Anti-Ms CD197 PE |
| Recommended Dilution | The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography. |
| Supplier | Nordic Biosite |
| Entrez Gene ID | 12775 |
| Format | PE |
| Immunogen | Murine CD197-transfected RBL-2H3 cells |
| Isotype | IgG2a k |
| Keywords | CD and Related Antigens & MHC (Rodent) |
| Notes | CD197 / CCR7 (chemokine receptor 7) is a seven membrane-spanning protein serving as a receptor for chemokines CCL19 and CCL21. It is expressed on most naive T cells, some hematopoietic stem cells, mature dendritic cells, NK cells and some memory T cells and B cells subsets. CD197 plays important roles in development of thymocytes, and regulating the recirculation and homing of lymphocytes and dendritic cells to secondary lymphoid organs. |
| Alias Names | CCR7, CC-CKR-7, EBI1 |
| Previous Article No | AFC-5316-2, AFC-RUQ7BR-0.1 |
| Product Type | Antibodies Primary |
| Protocol | Flow cytometry: Recommended dilution: 1-5 μg/ml. |
| Purification | Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography. |
| Research area | Immunology |
| Size | 0.1 mg |
| Source / Host | mouse |
| Species Reactivity | mouse |
| Storage | Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze. |
| Substrate / Buffer | Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Technical Specifications | The rat monoclonal antibody 4B12 recognizes an extracellular epitope of murine CD197 / CCR7 (chemokine receptor 7), a 43 kDa G-protein-coupled receptor for chemokines CCL19 and CCL21. |
| UniProt Number | P47774 |
| Product Page Updated | 2024-01-03T12:18:20.318Z |
