Article No
AFT-P9NCG2-100
MW | 50 kDa |
Application | ELISA, WB |
Article No | AFT-P9NCG2-100 |
Biosite Brand | Biosite |
Country Availability | all |
Clone | 0A10 |
Clone Type | monoclonal |
Conjugation | Unconjugated |
Description | ESR2 antibody |
Recommended Dilution | WB 1:500-1:2000 |
Supplier | Nordic Biosite |
Entrez Gene ID | 2100 |
Format | Liquid |
Gene Symbol | ESR2 |
Immunogen | estrogen receptor 2(ER beta) |
Isotype | IgG1 |
Notes | Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements(ERE) in an estrogen-dependent manner(PubMed:20074560). Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual. |
Alias Names | ESTRB, NR3A2 |
Previous Article No | AFT-B95072 |
Product Type | Antibodies Primary |
Purification | Protein A/G Purified |
Purity | ≥95% |
Research Area | Immunology, Metabolism, Neuroscience |
Shipping Information | BLUE ICE |
Size | 100ug |
Source / Host | mouse |
Species Reactivity | human, mouse |
Storage | -20°C |
UniProt Number | Q92731 |
Product Page Updated | 2024-02-02T15:01:32.974Z |