Article No
AG-20B-0071-C100
anti-MPC-2, mAb (JCM-1)
anti-MPC-2, mAb (JCM-1)
Antibodies Primary
Specifications
| Application | IP, WB |
| Article No | AG-20B-0071-C100 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | JCM-1 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | anti-MPC-2, mAb (JCM-1) |
| Supplier | Adipogen Life Sciences |
| Format | Liquid |
| Immunogen | Peptide coupled to KLH. |
| Isotype | IgG2b k |
| Notes | Monoclonal Antibody. Recognizes endogenous human and mouse MPC-2. Isotype: Mouse IgG2bkappa. Clone: JCM-1. Applications: IP, WB. Liquid. In PBS containing 25% glycerol and 0.02% sodium azide. Pyruvate is the end-product of glycolysis, a major substrate for oxidative metabolism, and a branching point for glucose, lactate, fatty acid and amino acid synthesis. The mitochondrial enzymes that metabolize pyruvate are physically separated from cytosolic pyruvate pools and rely on a membrane transport system to shuttle pyruvate across the impermeable inner mitochondrial membrane (IMM). Two proteins, mitochondrial pyruvate carriers MPC-1 and MPC-2, form a heterooligomeric complex in the IMM to facilitate pyruvate transport. This step is required for mitochondrial pyruvate oxidation and carboxylation-critical reactions in intermediary metabolism that are dysregulated in several common metabolic diseases.|Pyruvate is the end-product of glycolysis, a major substrate for oxidative metabolism, and a branching point for glucose, lactate, fatty acid and amino acid synthesis. The mitochondrial enzymes that metabolize pyruvate are physically separated from cytosolic pyruvate pools and rely on a membrane transport system to shuttle pyruvate across the impermeable inner mitochondrial membrane (IMM). Two proteins, mitochondrial pyruvate carriers MPC-1 and MPC-2, form a heterooligomeric complex in the IMM to facilitate pyruvate transport. This step is required for mitochondrial pyruvate oxidation and carboxylation-critical reactions in intermediary metabolism that are dysregulated in several common metabolic diseases. |
| Alias Names | Mitochondrial Pyruvate Carrier 2; Brain Protein 44 |
| Product Type | Antibodies Primary |
| Research area | Metabolism |
| Shipping Information | BLUE ICE |
| Size | 100 ug |
| Source / Host | mouse |
| Species Reactivity | human, mouse |
| Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Storage | -20°C, 4°C |
| Substrate / Buffer | Liquid. In PBS containing 25% glycerol and 0.02% sodium azide. |
| Technical Specifications | Monoclonal Antibody. Recognizes endogenous human and mouse MPC-2. Isotype: Mouse IgG2bkappa. Clone: JCM-1. Applications: IP, WB. Liquid. In PBS containing 25% glycerol and 0.02% sodium azide. Pyruvate is the end-product of glycolysis, a major substrate for oxidative metabolism, and a branching point for glucose, lactate, fatty acid and amino acid synthesis. The mitochondrial enzymes that metabolize pyruvate are physically separated from cytosolic pyruvate pools and rely on a membrane transport system to shuttle pyruvate across the impermeable inner mitochondrial membrane (IMM). Two proteins, mitochondrial pyruvate carriers MPC-1 and MPC-2, form a heterooligomeric complex in the IMM to facilitate pyruvate transport. This step is required for mitochondrial pyruvate oxidation and carboxylation-critical reactions in intermediary metabolism that are dysregulated in several common metabolic diseases. |
| Product Page Updated | 2024-02-01T08:25:01.492Z |
