Article No
AG-40B-0136-C010
Specifications
| MW | ~26kDa |
| Article No | AG-40B-0136-C010 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Concentration | 0.1 mg/ml |
| Description | Irisin (rec.) (CHO) |
| Supplier | Adipogen Life Sciences |
| Endotoxin | <0.01EU/µg purified protein (LAL test). |
| Entrez Gene ID | 252995 |
| Format | Powder |
| Gene Symbol | FNDC5 |
| Notes | Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone Irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure. Neuroprotectant in Alzheimer's disease.|Protein. Irisin (human, aa 32-143 /mouse, aa 29-140) is FLAG®-tagged at the N-terminus. Irisin has 100% identity between mouse, rat, monkey and human. Source: CHO cells. Endotoxin content: 95% (SDS-PAGE). Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone Irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure. |
| Alias Names | Fibronectin Type III Domain-containing Protein 5 (cleaved); Fibronectin Type III Repeat-containing Protein 2 (cleaved); FNDC5 (cleaved) |
| Product Type | Proteins & Peptides |
| Purity | >95% |
| Research area | Metabolism |
| Sequence | Irisin (human, aa 32-143 /mouse, aa 29-140) is FLAG®-tagged at the N-terminus. Irisin has 100% identity between mouse, rat, monkey and human. |
| Shipping Information | BLUE ICE |
| Size | 10 ug |
| Species Reactivity | human, mouse |
| Stability | Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
| Storage | -20°C, 4°C |
| Substrate / Buffer | Lyophilized. Contains PBS. |
| Technical Specifications | Protein. Irisin (human, aa 32-143 /mouse, aa 29-140) is FLAG®-tagged at the N-terminus. Irisin has 100% identity between mouse, rat, monkey and human. Source: CHO cells. Endotoxin content: 95% (SDS-PAGE). Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone Irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure. |
| UniProt Number | Q8NAU1 |
| Product Page Updated | 2024-02-01T08:25:01.492Z |
