Article No
AG-CN2-0101-M005
CAS No | 518-75-2 |
MW | 250.3 |
Additional Information | Solutions change color with changes in pH from yellow (pH 4.6) to red (pH 9.9). |
Article No | AG-CN2-0101-M005 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Description | Citrinin |
Supplier | Adipogen Life Sciences |
Additional Information | Solutions change color with changes in pH from yellow (pH 4.6) to red (pH 9.9). |
Format | Powder |
Notes | Antibiotic [1, 2]. Antiprotozoal. Antimicrobial [3, 6]. Cytotoxic and genotoxic in various mammalian cells [4]. Mitochondrial permeability transition pore (MPTP) activator [5-7]. Apoptosis inducer [7-9, 14]. ERK and JNK signaling pathways activator [10]. Nephrotoxic mycotoxin [11]. Suppresses NO and iNOS expression via inhibition of the JAK/STAT-1alpha and NF-kappaB signaling pathways [12]. Tubulin polymerization and mitotic spindle assembly inhibitor [13]. Increases reactive oxygen species (ROS) [14]. Induces cell cycle arrest at the G0/G1 and G2/M phase [13,14].|Chemical. CAS: 518-75-2. Formula: C13H14O5. MW: 250.3. Isolated from Penicillium citrinum strain FKI-4836. Antibiotic. Antiprotozoal. Antimicrobial. Cytotoxic and genotoxic in various mammalian cells. Mitochondrial permeability transition pore (MPTP) activator. Apoptosis inducer. ERK and JNK signaling pathways activator. Nephrotoxic mycotoxin. Suppresses NO and iNOS expression via inhibition of the JAK/STAT-1alpha and NF-kappaB signaling pathways. Tubulin polymerization and mitotic spindle assembly inhibitor. Increases reactive oxygen species (ROS). Induces cell cycle arrest at the G0/G1 and G2/M phase. |
Molecular Formula | C13H14O5 |
Alias Names | NSC 186; BRN 0088597; Antimycin |
Product Type | Chemicals & Biochemicals |
Protocol | Solutions change color with changes in pH from yellow (pH 4.6) to red (pH 9.9). |
Purity | >97% |
Research area | Cell Death |
Shipping Information | RT |
Size | 5 mg |
Solubility | Soluble in methanol, ethanol, methylene chloride, pyridine or dioxane. Insoluble in water, chloroform or hexane. |
Stability | Stable for at least 3 years after receipt when stored at -20°C. |
Storage | -20°C, 4°C |
Technical Specifications | Chemical. CAS: 518-75-2. Formula: C13H14O5. MW: 250.3. Isolated from Penicillium citrinum strain FKI-4836. Antibiotic. Antiprotozoal. Antimicrobial. Cytotoxic and genotoxic in various mammalian cells. Mitochondrial permeability transition pore (MPTP) activator. Apoptosis inducer. ERK and JNK signaling pathways activator. Nephrotoxic mycotoxin. Suppresses NO and iNOS expression via inhibition of the JAK/STAT-1alpha and NF-kappaB signaling pathways. Tubulin polymerization and mitotic spindle assembly inhibitor. Increases reactive oxygen species (ROS). Induces cell cycle arrest at the G0/G1 and G2/M phase. |
Product Page Updated | 2024-02-01T08:25:01.492Z |