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10,11-Dehydrocurvularin

Chemicals & Biochemicals

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Article No

AG-CN2-0165-M005

Size

5 mg

Shipping Information

Article No

AG-CN2-0165-M005

Size

5 mg

Specifications

CAS No	1095588-70-7
MW	290.3
Article No	AG-CN2-0165-M005
Country Availability	SE, FI, DK, NO, IS, EE, LV, LT
Description	10,11-Dehydrocurvularin
Supplier	Adipogen Life Sciences
Format	Powder
Notes	Antibiotic [1, 2, 6]. Antifungal [6]. Nematicidal [4]. Phytotoxic [3]. TGF-beta signaling inhibitor [9] Anticancer compound [5, 6, 8, 10]. Strong activator of the heat shock response [8]. Inhibitor of the appressorium formation of M. grisea [7]\|Chemical. CAS: 1095588-70-7. Formula: C16H18O5. MW: 290.3. Isolated from Aspergillus sp. Antibiotic. Antifungal. Nematicidal. Phytotoxic. TGF-beta signaling inhibitor Anticancer compound. Strong activator of the heat shock response. Inhibitor of the appressorium formation of M. grisea
Molecular Formula	C16H18O5
Alias Names	alpha,beta-Dehydrocurvularin
Product Type	Chemicals & Biochemicals
Purity	>95%
Research area	Immunology
Shipping Information	RT
Size	5 mg
Solubility	Soluble in ethanol, methanol or DMSO.
Stability	Stable for at least 2 years after receipt when stored at -20°C.
Storage	-20°C, 4°C
Technical Specifications	Chemical. CAS: 1095588-70-7. Formula: C16H18O5. MW: 290.3. Isolated from Aspergillus sp. Antibiotic. Antifungal. Nematicidal. Phytotoxic. TGF-beta signaling inhibitor Anticancer compound. Strong activator of the heat shock response. Inhibitor of the appressorium formation of M. grisea
Product Page Updated	2024-02-01T08:25:01.492Z

Documentation

Datasheet

MSDS

References

Curvularin. Part V. The compound C16H18O5, alphabeta-dehydrocurvularin: H.D. Munro, et al.; J. Chem. Soc. C 1967, 947 (1967) | Isolation of alpha,beta-dehydrocurvularin from Aspergillus aureofulgens: O. Caputo & F. Viola; Planta Med. 31, 31 (1977) | Brefeldin A and alpha,beta-dehydrocurvularin, two phytotoxins from Alternaria zinniae, a biocontrol agent of Xanthium occidentale: M. Vurro, et al.; Plant Sci. 138, 67 (1998) | Betagamma-dehydrocurvularin and related compounds as nematicides of Pratylenchus penetrans from the fungus Aspergillus sp.: M. Kusano, et al.; Biosci. Biotechnol. Biochem. 67, 1413 (2003) | Cytotoxic and other metabolites of Aspergillus inhabiting the rhizosphere of Sonoran desert plants: J. He, et al.; J. Nat. Prod. 67, 1985 (2004) | Isolation and difference in anti-Staphylococcus aureus bioactivity of curvularin derivates from fungus Eupenicillium sp.: L.W. Xie, et al.; Appl. Biochem. Biotechnol. 159, 284 (2009) | Alternariol monomethyl ether and alpha, beta-Dehydrocurvularin from endophytic Fungi Alternaria spp. inhibit appressorium formation of Magnaporthe grisea: Y.T. Jeon, et al.; J. Kor. Soc. Appl. Biol. Chem. 53, 39 (2010) | Characterization of the biosynthetic genes for 10,11-dehydrocurvularin, a heat shock response-modulating anticancer fungal polyketide from Aspergillus terreus: Y. Xu, et al.; Appl. Environ. Microbiol. 79, 2038 (2013) | Inhibition of TGF-beta signaling by the fungal lactones (S)-curvularin, dehydrocurvularin, oxacyclododecindione and galiellalactone: K. Rudolph, et al.; Cytokine 61, 285 (2013) | Metabolite profiling and biological activities of bioactive compounds produced by Chrysosporium lobatum strain BK-3 isolated from Kaziranga National Park, Assam, India: C.G. Kumar, et al.; Springerplus 2, 122 (2013)

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