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Betulinic acid (>97%)

Chemicals & Biochemicals

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Article No

AG-CN2-0417-M100

Size

100 mg

Shipping Information

Article No

AG-CN2-0417-M100

Size

100 mg

Specifications

CAS No	472-15-1
MW	456.7
Article No	AG-CN2-0417-M100
Country Availability	SE, FI, DK, NO, IS, EE, LV, LT
Description	Betulinic acid (>97%)
Supplier	Adipogen Life Sciences
Format	Powder
Notes	Anti-HIV compound [1]. Anticancer compound [2]. Apoptosis inducer [2]. Modulator of NF-kappaB [3,4,8]. Potent DNA topoisomerase II inhibitor [5]. Potent proteasome activator [6]. Antimalarial compound [7].\|Chemical. CAS: 472-15-1. Formula: C30H48O3. MW: 456.7. Isolated from Platanus acerifolia bark. Anti-HIV compound. Anticancer compound. Apoptosis inducer. Modulator of NF-kappaB. Potent DNA topoisomerase II inhibitor. Potent proteasome activator. Antimalarial compound.
Molecular Formula	C30H48O3
Alias Names	3beta-Hydroxy-20(29)-lupaene-28-oic acid
Product Type	Chemicals & Biochemicals
Purity	>97%
Research area	Cell Death
Shipping Information	RT
Size	100 mg
Solubility	Soluble in DMSO.
Stability	Stable for at least 2 years after receipt when stored at +4°C.
Storage	4°C
Technical Specifications	Chemical. CAS: 472-15-1. Formula: C30H48O3. MW: 456.7. Isolated from Platanus acerifolia bark. Anti-HIV compound. Anticancer compound. Apoptosis inducer. Modulator of NF-kappaB. Potent DNA topoisomerase II inhibitor. Potent proteasome activator. Antimalarial compound.
Product Page Updated	2024-02-01T08:25:01.492Z

Documentation

Datasheet

MSDS

References

Anti-AIDS agents, 11. Betulinic acid and platanic acid as anti-HIV principles from Syzigium claviflorum, and the anti-HIV activity of structurally related triterpenoids: T. Fujioka, et al.; J. Nat. Prod. 57, 243 (1994) | Discovery of betulinic acid as a selective inhibitor of human melanoma that functions by induction of apoptosis: E. Pisha, et al.; Nat. Med. 1, 1046 (1995) | Betulinic acid suppresses carcinogen-induced NF-kappa B activation through inhibition of I kappa B alpha kinase and p65 phosphorylation: abrogation of cyclooxygenase-2 and matrix metalloprotease-9: Y. Takada & B.B. Aggarwal: J. Immunol. 171, 3278 (2003) | Betulinic acid as new activator of NF-kappaB: molecular mechanisms and implications for cancer therapy: H. Kasperczyk, et al.; Oncogene 24, 6945 (2005) | Betulinic acid and its derivatives, potent DNA topoisomerase II inhibitors, from the bark of Bischofia javanica: S. Wada & R. Tanaka; Chem. Biodivers. 2, 689 (2005) | Activation and inhibition of the proteasome by betulinic acid and its derivatives: L. Huang, et al.; FEBS Lett. 581, 4955 (2007) | Antimalarial activity of betulinic acid and derivatives in vitro against Plasmodium falciparum and in vivo in P. berghei-infected mice: M.S. de Sa, et al.; Parasitol. Res. 105, 275 (2009) | Betulinic acid, a natural compound with potent anticancer effects: F.B. Mullauer, et al.; Anticancer Drugs 21, 215 (2010)

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