Article No
AG-CN2-0476-G001
Specifications
| CAS No | 473-98-3 |
| MW | 442.7 |
| Article No | AG-CN2-0476-G001 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Description | Betulin |
| Supplier | Adipogen Life Sciences |
| Format | Powder |
| Notes | Chemical. CAS: 473-98-3. Formula: C30H50O2. MW: 442.7. Isolated from Betulaceae family tree bark. Specific SREBPs (sterol regulatory element-binding proteins) inhibitor. Inhibits ER-Golgi translocation of SREBPs through binding to SCAP in an INSIG-dependent manner. Improves hyperlipidemia and insulin resistance and reduces atherosclerotic plaques. Lowers cholesterol levels through inhibition of SREBP-2 activation. Reduces weight gain and adipose tissue size in vivo. Increases oxygen consumption and energy expenditure. Increases UCP1/2 levels in brown adipose tissue (BAT) after cold stimulation. Anticancer compound. Apoptosis inducer. DNA topoisomerase II inhibitor. Anti-inflammatory compound. Shown to inhibit LPS-induced NO production through the TLR4/NF-kappaB signaling pathway. Antiviral compound.|Specific SREBPs (sterol regulatory element-binding proteins) inhibitor. Inhibits ER-Golgi translocation of SREBPs through binding to SCAP in an INSIG-dependent manner. Improves hyperlipidemia and insulin resistance and reduces atherosclerotic plaques. Lowers cholesterol levels through inhibition of SREBP-2 activation. Reduces weight gain and adipose tissue size in vivo. Increases oxygen consumption and energy expenditure. Increases UCP1/2 levels in brown adipose tissue (BAT) after cold stimulation. Anticancer compound. Apoptosis inducer. DNA topoisomerase II inhibitor. Anti-inflammatory compound. Shown to inhibit LPS-induced NO production through the TLR4/NF-kappaB signaling pathway. Antiviral compound. |
| Molecular Formula | C30H50O2 |
| Alias Names | Betulinol; Trochol; NSC 4644 |
| Product Type | Chemicals & Biochemicals |
| Purity | >98% |
| Research area | Cell Death |
| Shipping Information | RT |
| Size | 1 g |
| Solubility | Soluble in DMSO, DMF or ethanol. |
| Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Storage | 4°C |
| Technical Specifications | Chemical. CAS: 473-98-3. Formula: C30H50O2. MW: 442.7. Isolated from Betulaceae family tree bark. Specific SREBPs (sterol regulatory element-binding proteins) inhibitor. Inhibits ER-Golgi translocation of SREBPs through binding to SCAP in an INSIG-dependent manner. Improves hyperlipidemia and insulin resistance and reduces atherosclerotic plaques. Lowers cholesterol levels through inhibition of SREBP-2 activation. Reduces weight gain and adipose tissue size in vivo. Increases oxygen consumption and energy expenditure. Increases UCP1/2 levels in brown adipose tissue (BAT) after cold stimulation. Anticancer compound. Apoptosis inducer. DNA topoisomerase II inhibitor. Anti-inflammatory compound. Shown to inhibit LPS-induced NO production through the TLR4/NF-kappaB signaling pathway. Antiviral compound. |
| Product Page Updated | 2024-02-01T08:25:01.492Z |
