Article No
AG-CN2-0505-M001
CAS No | 58958-07-9 |
MW | 412.4 |
Article No | AG-CN2-0505-M001 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Description | (-)-Mitorubrinic acid |
Supplier | Adipogen Life Sciences |
Format | Powder |
Notes | Azaphilone fungal metabolite. Induces formation of chlamydospore-like cells in fungi. Trypsin inhibitor (IC50=16µg/ml). Mitorubrinic acid was shown to be a virulence factor of Penicillium marneffei by improving its intracellular survival in macrophages. P. marneffei is the most important thermal dimorphic fungus causing respiratory, skin and systemic mycosis in China and Southeast Asia. It is a common indicator disease of AIDS. Besides HIV positive patients, P. marneffei infections have been reported in other immunocompromised patients, such as transplant recipients, patients with systemic lupus erythematosus and on corticosteroid therapy.|Chemical. CAS: 58958-07-9. Formula: C21H16O9. MW: 412.4. Isolated from Penicillium sp. Azaphilone fungal metabolite. Induces formation of chlamydospore-like cells in fungi. Trypsin inhibitor (IC50=16µg/ml). Mitorubrinic acid was shown to be a virulence factor of Penicillium marneffei by improving its intracellular survival in macrophages. P. marneffei is the most important thermal dimorphic fungus causing respiratory, skin and systemic mycosis in China and Southeast Asia. It is a common indicator disease of AIDS. Besides HIV positive patients, P. marneffei infections have been reported in other immunocompromised patients, such as transplant recipients, patients with systemic lupus erythematosus and on corticosteroid therapy. |
Molecular Formula | C21H16O9 |
Alias Names | (R,E)-3-(7-((2,4-Dihydroxy-6-methylbenzoyl)oxy)-7-methyl-6,8-dioxo-7,8-dihydro-6H-isochromen-3-yl)acrylic acid |
Product Type | Chemicals & Biochemicals |
Purity | >90% |
Research Area | Immunology |
Shipping Information | RT |
Size | 1 mg |
Solubility | Soluble in DMSO, ethanol or methanol. |
Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Storage | -20°C, 4°C |
Technical Specifications | Chemical. CAS: 58958-07-9. Formula: C21H16O9. MW: 412.4. Isolated from Penicillium sp. Azaphilone fungal metabolite. Induces formation of chlamydospore-like cells in fungi. Trypsin inhibitor (IC50=16µg/ml). Mitorubrinic acid was shown to be a virulence factor of Penicillium marneffei by improving its intracellular survival in macrophages. P. marneffei is the most important thermal dimorphic fungus causing respiratory, skin and systemic mycosis in China and Southeast Asia. It is a common indicator disease of AIDS. Besides HIV positive patients, P. marneffei infections have been reported in other immunocompromised patients, such as transplant recipients, patients with systemic lupus erythematosus and on corticosteroid therapy. |
Product Page Updated | 2024-02-01T08:25:01.492Z |