Article No
AG-CN2-9003-M001
Ganglioside GD1a . disodium salt (bovine brain)
Ganglioside GD1a . disodium salt (bovine brain)
Chemicals & Biochemicals
Specifications
| CAS No | 12707-58-3 |
| MW | 1836.1 . 46.0 (calculated on sphingosine C18:1 and stearic acid) |
| Article No | AG-CN2-9003-M001 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Description | Ganglioside GD1a . disodium salt (bovine brain) |
| Supplier | Adipogen Life Sciences |
| Endotoxin | Not detectable. |
| Format | Powder |
| Notes | Chemical. CAS: 12707-58-3. Formula: C84H146N4O39 . 2Na. MW: 1836.1 . 46.0 (calculated on sphingosine C18:1 and stearic acid). Isolated from bovine brain. Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosides has been linked to several diseases. Ganglioside GD1a is the major ganglioside of the nervous system. It is converted to GM1 by bacterial, viral and mammalian sialidases. It is a differentiation marker for cell growth.|Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosides has been linked to several diseases. Ganglioside GD1a is the major ganglioside of the nervous system. It is converted to GM1 by bacterial, viral and mammalian sialidases. It is a differentiation marker for cell growth. |
| Molecular Formula | C84H146N4O39 . 2Na |
| Alias Names | GD1a . 2Na; Disialoganglioside GD1a . 2Na |
| Product Type | Chemicals & Biochemicals |
| Purity | >98% |
| Research area | Inflammation |
| Sequence | Structure: IV3Neu5AcII3NeuAcGgOse4Cer; alpha-Neu5Ac-(2-3)-beta-Gal-(1-3)-beta-GalNAc-(1-4)-[alpha-Neu5Ac-(2-3)-]beta-Gal-(1-4)-beta-Glc-(1-1)-Cer; Cer: Sphingosine C18:1-C20:1, ~1:1 to 1:3 by vol.; stearic acid over 90% |
| Shipping Information | RT |
| Size | 1 mg |
| Solubility | Soluble in water (micellar aggregates) or chloroform:methanol (2:1). |
| Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Storage | -20°C, 4°C |
| Substrate / Buffer | Lyophilized. |
| Technical Specifications | Chemical. CAS: 12707-58-3. Formula: C84H146N4O39 . 2Na. MW: 1836.1 . 46.0 (calculated on sphingosine C18:1 and stearic acid). Isolated from bovine brain. Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosides has been linked to several diseases. Ganglioside GD1a is the major ganglioside of the nervous system. It is converted to GM1 by bacterial, viral and mammalian sialidases. It is a differentiation marker for cell growth. |
| Product Page Updated | 2024-02-01T08:25:01.492Z |
