Article No
AG-CN2-9006-M001
Ganglioside GT1b . trisodium salt (bovine brain)
Ganglioside GT1b . trisodium salt (bovine brain)
Chemicals & Biochemicals
Specifications
| CAS No | 59247-13-1 |
| MW | 2126.3 . 69.0 (calculated on sphingosine C18:1 and stearic acid) |
| Article No | AG-CN2-9006-M001 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Description | Ganglioside GT1b . trisodium salt (bovine brain) |
| Supplier | Adipogen Life Sciences |
| Endotoxin | Not detectable. |
| Format | Powder |
| Notes | Chemical. CAS: 59247-13-1. Formula: C95H162N5O47 . 3Na. MW: 2126.3 . 69.0 (calculated on sphingosine C18:1 and stearic acid). Isolated from bovine brain. Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosides has been linked to several diseases. Ganglioside GT1b binds botulinum and tetanus neurotoxins and it prevents neurotoxicity of glutamate on neuronal cells.|Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosides has been linked to several diseases. Ganglioside GT1b binds botulinum and tetanus neurotoxins and it prevents neurotoxicity of glutamate on neuronal cells. |
| Molecular Formula | C95H162N5O47 . 3Na |
| Alias Names | GT1b . 3Na; Trisialoganglioside GT1b . 3Na |
| Product Type | Chemicals & Biochemicals |
| Purity | >98% |
| Research area | Inflammation |
| Sequence | Structure: IV3Neu5AcII3NeuAc2GgOse4Cer; alpha-Neu5Ac-(2-3)-beta-Gal-(1-3)-beta-GalNAc-(1-4)-[alpha-Neu5Ac-(2-8)-alpha-Neu5Ac-(2-3)-]beta-Gal-(1-4)-beta-Glc-(1-1)-Cer; Cer: Sphingosine C18:1-C20:1, ~1:1 to 1:3 by vol.; stearic acid over 90% |
| Shipping Information | RT |
| Size | 1 mg |
| Solubility | Soluble in water (micellar aggregates) or chloroform:methanol (2:1). |
| Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Storage | -20°C, 4°C |
| Substrate / Buffer | Lyophilized |
| Technical Specifications | Chemical. CAS: 59247-13-1. Formula: C95H162N5O47 . 3Na. MW: 2126.3 . 69.0 (calculated on sphingosine C18:1 and stearic acid). Isolated from bovine brain. Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosides has been linked to several diseases. Ganglioside GT1b binds botulinum and tetanus neurotoxins and it prevents neurotoxicity of glutamate on neuronal cells. |
| Product Page Updated | 2024-02-01T08:25:01.492Z |
