Article No
AG-CN2-9007-C100
Ganglioside GQ1b . tetrasodium salt (bovine brain)
Ganglioside GQ1b . tetrasodium salt (bovine brain)
Chemicals & Biochemicals
Specifications
| CAS No | 68652-37-9 |
| MW | 2416.6 . 92.0 (calculated on sphingosine C18:1 and stearic acid) |
| Article No | AG-CN2-9007-C100 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Description | Ganglioside GQ1b . tetrasodium salt (bovine brain) |
| Supplier | Adipogen Life Sciences |
| Endotoxin | Not detectable. |
| Format | Powder |
| Notes | Chemical. CAS: 68652-37-9. Formula: C106H178N6O55 . 4Na. MW: 2416.6 . 92.0 (calculated on sphingosine C18:1 and stearic acid). Isolated from bovine brain. Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosides has been linked to several diseases. Ganglioside GQ1b specifically promotes neural differentiation of human neuroblastoma cells. Anti-GQ1b antibodies are present in serum from Miller-Fisher syndrome patients.|Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosides has been linked to several diseases. Ganglioside GQ1b specifically promotes neural differentiation of human neuroblastoma cells. Anti-GQ1b antibodies are present in serum from Miller-Fisher syndrome patients. |
| Molecular Formula | C106H178N6O55 . 4Na |
| Alias Names | GQ1b . 4Na; Tetrasialoganglioside GQ1b . 4Na |
| Product Type | Chemicals & Biochemicals |
| Purity | >98% |
| Research area | Inflammation |
| Sequence | Structure: IV3Neu5Ac2II3NeuAc2GgOse4Cer; alpha-Neu5Ac-(2-8)-alpha-Neu5Ac-(2-3)-beta-Gal-(1-3)-beta-GalNAc-(1-4)-[alpha-Neu5Ac-(2-8)-alpha-Neu5Ac-(2-3)-]beta-Gal-(1-4)-beta-Glc-(1-1)-Cer; Cer: Sphingosine C18:1-C20:1, ~1:1 to 1:3 by vol.; stearic acid over 90% |
| Shipping Information | RT |
| Size | 100 ug |
| Solubility | Soluble in water (micellar aggregates) or chloroform:methanol (2:1). |
| Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Storage | -20°C, 4°C |
| Substrate / Buffer | Lyophilized. |
| Technical Specifications | Chemical. CAS: 68652-37-9. Formula: C106H178N6O55 . 4Na. MW: 2416.6 . 92.0 (calculated on sphingosine C18:1 and stearic acid). Isolated from bovine brain. Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosides has been linked to several diseases. Ganglioside GQ1b specifically promotes neural differentiation of human neuroblastoma cells. Anti-GQ1b antibodies are present in serum from Miller-Fisher syndrome patients. |
| Product Page Updated | 2024-02-01T08:25:01.492Z |
