Article No
AG-CP3-7001-M100
Specifications
| CAS No | 26305-03-3 |
| MW | 685.9 |
| Article No | AG-CP3-7001-M100 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Description | Pepstatin A |
| Supplier | Adipogen Life Sciences |
| Format | Powder |
| Notes | Chemical. CAS: 26305-03-3. Formula: C34H63N5O9. MW: 685.9. Synthetic. Tight-binding, reversible, highly selective inhibitor of acid proteases (aspartyl peptidases), like pepsin, gastricsin, cathepsin E and D, renin, chymosin, bacterial aspartic proteinases and HIV proteases. Does not inhibit thiol proteases, neutral proteases or serine proteases. Widely used as a research tool in studies of protease mechanisms and biological functions. Solubilized gamma-secretase and retroviral protease inhibitor. Shows antibacterial, antifungal and antiparasitic activity. Suppresses p53-dependent apoptosis in lymphoid cells as well as TNFalpha-induced apoptosis in U937 cells. Inhibits degradation of autophagic cargo inside autophagolysosomes.|Tight-binding, reversible, highly selective inhibitor of acid proteases (aspartyl peptidases), like pepsin, gastricsin, cathepsin E and D, renin, chymosin, bacterial aspartic proteinases and HIV proteases. Does not inhibit thiol proteases, neutral proteases or serine proteases. Widely used as a research tool in studies of protease mechanisms and biological functions. Solubilized gamma-secretase and retroviral protease inhibitor. Shows antibacterial, antifungal and antiparasitic activity. Suppresses p53-dependent apoptosis in lymphoid cells as well as TNFalpha-induced apoptosis in U937 cells. Inhibits degradation of autophagic cargo inside autophagolysosomes. |
| Molecular Formula | C34H63N5O9 |
| Alias Names | i-Valeryl-L-Val-L-Val-AHMHA-L-Ala-AHMHA; Procidin S 735A; NSC 272671 |
| Product Type | Chemicals & Biochemicals |
| Purity | >98% |
| Research area | Cell Death |
| Sequence | Iva-Val-Val-Sta-Ala-Sta |
| Shipping Information | RT |
| Size | 100 mg |
| Solubility | Soluble in DMSO (10mg/ml), ethanol (1mg/ml, gentle warming), methanol or acetic acid. |
| Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Storage | -20°C, 4°C |
| Technical Specifications | Chemical. CAS: 26305-03-3. Formula: C34H63N5O9. MW: 685.9. Synthetic. Tight-binding, reversible, highly selective inhibitor of acid proteases (aspartyl peptidases), like pepsin, gastricsin, cathepsin E and D, renin, chymosin, bacterial aspartic proteinases and HIV proteases. Does not inhibit thiol proteases, neutral proteases or serine proteases. Widely used as a research tool in studies of protease mechanisms and biological functions. Solubilized gamma-secretase and retroviral protease inhibitor. Shows antibacterial, antifungal and antiparasitic activity. Suppresses p53-dependent apoptosis in lymphoid cells as well as TNFalpha-induced apoptosis in U937 cells. Inhibits degradation of autophagic cargo inside autophagolysosomes. |
| Product Page Updated | 2024-02-01T08:25:01.492Z |
