Article No
AG-CR1-0018-M025
CAS No | 214358-33-5 |
MW | 177.3 . 72.9 |
Article No | AG-CR1-0018-M025 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Description | 1400W . dihydrochloride |
Supplier | Adipogen Life Sciences |
Format | Powder |
Notes | A slow, tight binding and highly selective inhibitor of iNOS (inducible nitric oxide synthase/NOS II) (Kd < 7 nM) [1, 3, 4, 6]. Weak and reversible inhibition of nNOS (neuronal nitric oxide synthase/NOS I) (Ki < 2) and eNOS (endothelial nitric oxide synthase/NOS III) (Ki < 50 µM) [1]. Inhibits tumor growth [2]. Increases vasoconstriction to noradrenaline [7]. Improves contractile function [8]. Improves stroke outcome and decreases glutamate release [9]. Anti-inflammatory [10]. Significant AMPK activity suppressor. Review [5].|Chemical. CAS: 214358-33-5. Formula: C10H15N3 . 2HCl. MW: 177.3 . 72.9. A slow, tight binding and highly selective inhibitor of iNOS (inducible nitric oxide synthase/NOS II) (Kd < 7 nM). Weak and reversible inhibition of nNOS (neuronal nitric oxide synthase/NOS I) (Ki < 2) and eNOS (endothelial nitric oxide synthase/NOS III) (Ki < 50 µM). Inhibits tumor growth. Increases vasoconstriction to noradrenaline. Improves contractile function. Improves stroke outcome and decreases glutamate release. Anti-inflammatory. Review. |
Molecular Formula | C10H15N3 . 2HCl |
Alias Names | N-(3-(Aminomethyl)benzyl)acetamidine . 2HCl |
Product Type | Chemicals & Biochemicals |
Purity | >98% |
Research area | Inflammation |
Shipping Information | RT |
Size | 25 mg |
Solubility | Soluble in water, methanol or DMSO. |
Stability | Stable for at least 2 years after receipt when stored at +4°C. |
Storage | 4°C |
Technical Specifications | Chemical. CAS: 214358-33-5. Formula: C10H15N3 . 2HCl. MW: 177.3 . 72.9. A slow, tight binding and highly selective inhibitor of iNOS (inducible nitric oxide synthase/NOS II) (Kd < 7 nM). Weak and reversible inhibition of nNOS (neuronal nitric oxide synthase/NOS I) (Ki < 2) and eNOS (endothelial nitric oxide synthase/NOS III) (Ki < 50 µM). Inhibits tumor growth. Increases vasoconstriction to noradrenaline. Improves contractile function. Improves stroke outcome and decreases glutamate release. Anti-inflammatory. Review. |
Product Page Updated | 2024-02-01T08:25:01.492Z |