Article No
AM1835a
MW | 68678 |
NCBI Number | NP_001125.1 |
Accession Number | P02771 |
Application | WB |
Article No | AM1835a |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
Clone | 143CT50.11.8 |
Clone Type | monoclonal |
Conjugation | Unconjugated |
Description | AFP Antibody (N-term) |
Recommended Dilution | 1:1000 |
Supplier | Abgent |
Entrez Gene ID | 174 |
Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
Isotype | IgM |
Keywords | Primary Antibodies;Cancer;Cardiovascular;Developmental Biology;Signal Transduction |
Notes | alpha 1 Fetoprotein encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. |
Alias Names | Alpha-fetoprotein, Alpha-1-fetoprotein, Alpha-fetoglobulin, AFP, HPAFP |
Product Type | Antibodies Primary |
Size | 400 µl |
Source / Host | mouse |
Species Reactivity | human |
Substrate / Buffer | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
Technical Specifications | This AFP antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 56-85 amino acids from the N-terminal region of human AFP. |
Product Page Updated | 2023-11-23T14:38:54.086Z |