Article No
AM2023a
Specifications
| MW | 33295 |
| NCBI Number | NP_001019245.1;NP_001019246.1;NP_008826.1 |
| Accession Number | P50135 |
| Application | WB |
| Article No | AM2023a |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | 432CT31.4.2 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | HNMT Antibody(Ascites) |
| Recommended Dilution | 1:100~8000 |
| Supplier | Abgent |
| Entrez Gene ID | 3176 |
| Format | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
| Isotype | IgG1 |
| Keywords | Primary Antibodies;Neuroscience |
| Notes | In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. |
| Alias Names | Histamine N-methyltransferase, HMT, HNMT |
| Product Type | Antibodies Primary |
| Research area | Neuroscience |
| Size | 100 µl |
| Source / Host | mouse |
| Species Reactivity | human |
| Substrate / Buffer | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
| Technical Specifications | Purified His-tagged HNMT protein(Fragment) was used to produced this monoclonal antibody. |
| Product Page Updated | 2023-11-23T14:38:54.086Z |
