Article No
AM2044a
FCGR3A Antibody
FCGR3A Antibody (Ascites)
Antibodies Primary
Specifications
| MW | 29089 |
| NCBI Number | NP_000560.5;NP_001121064.1;NP_001121065.1;NP_001121067.1;NP_001121068.1 |
| Accession Number | P08637 |
| Application | WB |
| Article No | AM2044a |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | 441CT4.2.1 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | FCGR3A Antibody (Ascites) |
| Recommended Dilution | 1:500~1000 |
| Supplier | Abgent |
| Entrez Gene ID | 2214 |
| Format | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
| Isotype | IgG1 |
| Keywords | Primary Antibodies;Immunology;Signal Transduction |
| Notes | This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Alias Names | Low affinity immunoglobulin gamma Fc region receptor III-A, CD16a antigen, Fc-gamma RIII-alpha, Fc-gamma RIII, Fc-gamma RIIIa, FcRIII, FcRIIIa, FcR-10, IgG Fc receptor III-2, CD16a, FCGR3A, CD16A, FCG3, FCGR3, IGFR3 |
| Product Type | Antibodies Primary |
| Research area | Immunology |
| Size | 100 µl |
| Source / Host | mouse |
| Species Reactivity | human |
| Substrate / Buffer | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
| Technical Specifications | This FCGR3A antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 60-88 amino acids from human FCGR3A. |
| Product Page Updated | 2023-11-23T14:38:54.086Z |
