Article No
AMB-5BHQLZ-100
FAK Primary Antibody
FAK Primary Antibody
Antibodies Primary
Specifications
| MW | 119kDa |
| Application | WB, ELISA |
| Article No | AMB-5BHQLZ-100 |
| Biosite Brand | Biosite mAb |
| Country Availability | all |
| Clone | 10H7A6 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | FAK Primary Antibody |
| Supplier | Nordic Biosite |
| Entrez Gene ID | 5747 |
| Format | Purified antibody in PBS containing 0.03% sodium azide. |
| Immunogen | Purified recombinant fragment of human FAK expressed in E. Coli. |
| Isotype | IgG1 |
| Notes | This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. At least four transcript variants encoding four different isoforms have been found for this gene, but the full-length natures of only two of them have been determined. Tissue specificity: Expressed in all organs tested, in lymphoid cell lines, but most abundantly in brain.RD: Focal adhesion kinase 1 (FAK) is a ubiquitously expressed non-receptor protein tyrosine kinase that is concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. This cellular localization is directed by a |
| Alias Names | FAK; FADK; FAK1; FRNK; pp125FAK; PTK2 |
| Previous Article No | AMB-8491 |
| Product Type | Antibodies Primary |
| Protocol | ELISA: 1/10000; WB: 1/500 - 1/2000 |
| Size | 100µl |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C -20°C for long term storage |
| Substrate / Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Technical Specifications | ELISA: 1/10000; WB: 1/500 - 1/2000 |
| Product Page Updated | 2024-01-25T14:27:22.065Z |
