Article No
AMB-HUAIJE-100
4E-BP1 Primary Antibody
4E-BP1 Primary Antibody
Antibodies Primary
Specifications
| Application | WB, ELISA |
| Article No | AMB-HUAIJE-100 |
| Biosite Brand | Biosite mAb |
| Country Availability | all |
| Clone | 4B6G10 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | 4E-BP1 Primary Antibody |
| Supplier | Nordic Biosite |
| Entrez Gene ID | 1978 |
| Format | Ascitic fluid containing 0.03% sodium azide. |
| Immunogen | Purified recombinant fragment of 4E-BP1 expressed in E. Coli. |
| Isotype | IgG1 |
| Notes | 4E-BP1(eukaryotic translation Initiation Factor 4E Binding Protein 1),also called ELF4EBP1/BP-1/PHAS-I ,which is located on chromosome 8p12, with 118-amino acid protein (about 13kDa). Binding of eIF4EBP1 to eIF4E is reversible and is dependent on the phosphorylation status of eIF4EBP1. Non phosphorylated eIF4EBP1 will bind strongly to eIF4E while(24kDa), the phosphorylated form will not. Akt, TOR, MAP kinase, S6 kinase, and Cdc2 are known kinases capable of inactivating eIF4EBP1 binding to eIF4E by phosphorylating either threonines 35, 45, 69 or serine 64. Although, not all phosphorylation events equally block the eIF4EBP1-eIF4E interaction. |
| Alias Names | BP-1; 4EBP1; 4E-BP1; PHAS-I; MGC4316; EIF4EBP1 |
| Previous Article No | AMB-8168 |
| Product Type | Antibodies Primary |
| Protocol | ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000 |
| Size | 100µl |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C -20°C for long term storage |
| Substrate / Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Technical Specifications | ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000 |
| Product Page Updated | 2024-01-25T14:27:22.065Z |
