Article No
ANC-260-040
anti-CD8-alpha (mouse), mAb (53-6) (FITC)
anti-CD8-alpha (mouse), mAb (53-6) (FITC)
Antibodies Primary
Specifications
| Application | ELISA, FC |
| Article No | ANC-260-040 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 53-6 |
| Clone Type | monoclonal |
| Conjugation | FITC |
| Description | anti-CD8-alpha (mouse), mAb (53-6) (FITC) |
| Supplier | Adipogen Life Sciences |
| Format | Liquid |
| Immunogen | murine thymocytes/splenocytes. |
| Isotype | IgG2a k |
| Notes | CD8 identifies cytotoxic/suppressor T cells that interact with MHC Class I bearing targets. CD8 is thought to play a role in the process of T cell mediated killing. CD8-alpha chains binds to Class I MHC molecules alpha-3 domains. Defects in CD8A are a cause of familial CD8 deficiency [MIM:608957]. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections.|Monoclonal Antibody. Isotype: Rat IgG2akappa. Clone: 53-6. Applications: ELISA, FACS. 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative). CD8 identifies cytotoxic/suppressor T cells that interact with MHC Class I bearing targets. CD8 is thought to play a role in the process of T cell mediated killing. CD8-alpha chains binds to Class I MHC molecules alpha-3 domains. Defects in CD8A are a cause of familial CD8 deficiency. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections. |
| Product Type | Antibodies Primary |
| Research area | Immunology |
| Shipping Information | BLUE ICE |
| Size | 120 tests |
| Source / Host | rat |
| Species Reactivity | mouse |
| Stability | Stable for at least 1 year after receipt when stored at +4°C. |
| Storage | 4°C |
| Substrate / Buffer | 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative). |
| Technical Specifications | Monoclonal Antibody. Isotype: Rat IgG2akappa. Clone: 53-6. Applications: ELISA, FACS. 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative). CD8 identifies cytotoxic/suppressor T cells that interact with MHC Class I bearing targets. CD8 is thought to play a role in the process of T cell mediated killing. CD8-alpha chains binds to Class I MHC molecules alpha-3 domains. Defects in CD8A are a cause of familial CD8 deficiency. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections. |
| Product Page Updated | 2024-02-01T08:25:01.492Z |
