Article No
ANC-272-020
anti-CD272 [BTLA] (human), mAb (ANC6E9)
anti-CD272 [BTLA] (human), mAb (ANC6E9)
Antibodies Primary
Specifications
| Application | Block, ELISA, FC |
| Article No | ANC-272-020 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | ANC6E9 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | anti-CD272 [BTLA] (human), mAb (ANC6E9) |
| Supplier | Adipogen Life Sciences |
| Format | Liquid |
| Immunogen | Recombinant extracellular human CD272. |
| Isotype | IgG1 k |
| Notes | Human CD272 (BTLA; B and T Lymphocyte Attenuator) is a member of the immunoglobulin superfamily and has sequence homology to PD-1 and CTLA-4. It is expressed on T and B lymphocytes and other hemopoetic lineages. Engagement of this molecule by its ligand CD270 (HVEM) can downregulate activated T and B cell responses. CD272 levels on antigen specific CD8+ T cells have been reported to decrease in viral specific, but not melanoma specific activated lines. Polymorphism of the CD272 molecule has been linked to rheumatoid arthritis.|Monoclonal Antibody. Isotype: Mouse IgG1kappa. Clone: ANC6E9. Applications: ELISA, FACS, FUNC (Blocking). 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 0.5% Gentamicin sulfate Human CD272 (BTLA; B and T Lymphocyte Attenuator) is a member of the immunoglobulin superfamily and has sequence homology to PD-1 and CTLA-4. It is expressed on T and B lymphocytes and other hemopoetic lineages. Engagement of this molecule by its ligand CD270 (HVEM) can downregulate activated T and B cell responses. CD272 levels on antigen specific CD8+ T cells have been reported to decrease in viral specific, but not melanoma specific activated lines. Polymorphism of the CD272 molecule has been linked to rheumatoid arthritis. |
| Alias Names | BTLA; B- and T-lymphocyte Attenuator |
| Product Type | Antibodies Primary |
| Research area | Immunology |
| Shipping Information | BLUE ICE |
| Size | 100 µg |
| Source / Host | mouse |
| Species Reactivity | human |
| Stability | Stable for at least 1 year after receipt when stored at +4°C. |
| Storage | 4°C |
| Substrate / Buffer | 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 0.5% Gentamicin sulfate |
| Technical Specifications | Monoclonal Antibody. Isotype: Mouse IgG1kappa. Clone: ANC6E9. Applications: ELISA, FACS, FUNC (Blocking). 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 0.5% Gentamicin sulfate Human CD272 (BTLA; B and T Lymphocyte Attenuator) is a member of the immunoglobulin superfamily and has sequence homology to PD-1 and CTLA-4. It is expressed on T and B lymphocytes and other hemopoetic lineages. Engagement of this molecule by its ligand CD270 (HVEM) can downregulate activated T and B cell responses. CD272 levels on antigen specific CD8+ T cells have been reported to decrease in viral specific, but not melanoma specific activated lines. Polymorphism of the CD272 molecule has been linked to rheumatoid arthritis. |
| Product Page Updated | 2024-02-01T08:25:01.492Z |
