Article No
ANC-279-020
Application | ELISA, FC |
Article No | ANC-279-020 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Clone | ANC4H6 |
Clone Type | monoclonal |
Conjugation | Unconjugated |
Description | anti-CD279 [PD-1] (human), mAb (ANC4H6) |
Supplier | Adipogen Life Sciences |
Format | Liquid |
Immunogen | Recombinant human CD279. |
Isotype | IgG1 k |
Notes | Human CD279 (PD-1; Programmed Death 1) is a 55kDa Ig superfamily member with similarity to CD28 and CD152 (CTLA-4). It is expressed on activated T and B and myeloid cells and engagement by its ligands PD-L1 (CD274; B7-H1) or PD-L2 (B7-DC) can inhibit proliferation and cytokine expression. In mice blockade of PD-1 ligand interaction has been used to augment T cell anti-cancer responses.|Monoclonal Antibody. Isotype: Mouse IgG1kappa. Clone: ANC4H6. Applications: ELISA, FACS. 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 0.5% Gentamicin sulfate Human CD279 (PD-1; Programmed Death 1) is a 55kDa Ig superfamily member with similarity to CD28 and CD152 (CTLA-4). It is expressed on activated T and B and myeloid cells and engagement by its ligands PD-L1 (CD274; B7-H1) or PD-L2 (B7-DC) can inhibit proliferation and cytokine expression. In mice blockade of PD-1 ligand interaction has been used to augment T cell anti-cancer responses. |
Alias Names | PD-1; Programmed Cell Death Protein 1 |
Product Type | Antibodies Primary |
Research area | Immunology |
Shipping Information | BLUE ICE |
Size | 100 µg |
Source / Host | mouse |
Species Reactivity | human |
Stability | Stable for at least 1 year after receipt when stored at +4°C. |
Storage | 4°C |
Substrate / Buffer | 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 0.5% Gentamicin sulfate |
Technical Specifications | Monoclonal Antibody. Isotype: Mouse IgG1kappa. Clone: ANC4H6. Applications: ELISA, FACS. 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 0.5% Gentamicin sulfate Human CD279 (PD-1; Programmed Death 1) is a 55kDa Ig superfamily member with similarity to CD28 and CD152 (CTLA-4). It is expressed on activated T and B and myeloid cells and engagement by its ligands PD-L1 (CD274; B7-H1) or PD-L2 (B7-DC) can inhibit proliferation and cytokine expression. In mice blockade of PD-1 ligand interaction has been used to augment T cell anti-cancer responses. |
Product Page Updated | 2024-02-01T08:25:01.492Z |