Article No
ANC-333-030
anti-FOXP3 (human), mAb (ANCFX2D7) (Biotin)
anti-FOXP3 (human), mAb (ANCFX2D7) (Biotin)
Antibodies Primary
Specifications
| Application | ELISA, FC |
| Article No | ANC-333-030 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | ANCFX2D7 |
| Clone Type | monoclonal |
| Conjugation | Biotin |
| Description | anti-FOXP3 (human), mAb (ANCFX2D7) (Biotin) |
| Supplier | Adipogen Life Sciences |
| Format | Liquid |
| Immunogen | Recombinant human FOXP3. |
| Isotype | IgG1 k |
| Notes | FOXP3 is involved in immune system responses. It functions as the master regulator in the development and function of regulatory T cells. FOX proteins belong to the forkhead/winged-helix family of transcriptional regulators and are presumed to exert control via similar DNA binding interactions during transcription. Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX); also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema.|Monoclonal Antibody. Recognizes human FOXP3. Isotype: Mouse IgG1kappa. Clone: ANCFX2D7. Applications: ELISA, FACS. 50mM Sodium phosphate pH7.5, 100mM Potassium chloride, 150mM NaCl, 5% glycerol, 0.2%BSA, 0.04% sodium azide (as preservative). FOXP3 is involved in immune system responses. It functions as the master regulator in the development and function of regulatory T cells. FOX proteins belong to the forkhead/winged-helix family of transcriptional regulators and are presumed to exert control via similar DNA binding interactions during transcription. Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX); also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema. |
| Alias Names | Forkhead Box Protein P3; Scurfin; IPEX, JM2 |
| Product Type | Antibodies Primary |
| Purity | >95% |
| Research area | Immunology |
| Shipping Information | BLUE ICE |
| Size | 100 µg |
| Source / Host | mouse |
| Species Reactivity | human |
| Stability | Stable for at least 1 year after receipt when stored at +4°C. |
| Storage | 4°C |
| Substrate / Buffer | 50mM Sodium phosphate pH7.5, 100mM Potassium chloride, 150mM NaCl, 5% glycerol, 0.2%BSA, 0.04% sodium azide (as preservative). |
| Technical Specifications | Monoclonal Antibody. Recognizes human FOXP3. Isotype: Mouse IgG1kappa. Clone: ANCFX2D7. Applications: ELISA, FACS. 50mM Sodium phosphate pH7.5, 100mM Potassium chloride, 150mM NaCl, 5% glycerol, 0.2%BSA, 0.04% sodium azide (as preservative). FOXP3 is involved in immune system responses. It functions as the master regulator in the development and function of regulatory T cells. FOX proteins belong to the forkhead/winged-helix family of transcriptional regulators and are presumed to exert control via similar DNA binding interactions during transcription. Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX); also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema. |
| Product Page Updated | 2024-02-01T08:25:01.492Z |
