Article No
AP12289B
Specifications
| MW | 53696 |
| NCBI Number | NP_001121904.1;NP_001264154.1;NP_066024.1 |
| Accession Number | Q9H227 |
| Application | WB |
| Article No | AP12289B |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | RB31046 |
| Clone Type | polyclonal |
| Conjugation | Unconjugated |
| Description | GBA3 Antibody (C-term) |
| Recommended Dilution | 1:1000 |
| Supplier | Abgent |
| Entrez Gene ID | 57733 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Isotype | IgG |
| Keywords | Primary Antibodies;Metabolism;Signal Transduction |
| Notes | GBA3, or cytosolic beta-glucosidase (EC 3.2.1.21), is a predominantly liver enzyme that efficiently hydrolyzes beta-D-glucoside and beta-D-galactoside, but not any known physiologic beta-glycoside, suggesting that it may be involved in detoxification of plant glycosides (de Graaf et al., 2001 [PubMed 11389701]). GBA3 also has significant neutral glycosylceramidase activity (EC 3.2.1.62), suggesting that it may be involved in a nonlysosomal catabolic pathway of glucosylceramide metabolism (Hayashi et al., 2007 [PubMed 17595169]). |
| Alias Names | Cytosolic beta-glucosidase, Cytosolic beta-glucosidase-like protein 1, GBA3, CBG, CBGL1 |
| Product Type | Antibodies Primary |
| Research area | Metabolism |
| Size | 400 µl |
| Source / Host | rabbit |
| Species Reactivity | human |
| Substrate / Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Technical Specifications | This GBA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-325 amino acids from the C-terminal region of human GBA3. |
| Product Page Updated | 2023-11-23T14:38:54.086Z |
