Article No
AP18145b-ev
Specifications
| MW | 103635 |
| NCBI Number | NP_055660.1 |
| Accession Number | Q92562 |
| Application | WB |
| Article No | AP18145b-ev |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | RB24204 |
| Clone Type | polyclonal |
| Conjugation | Unconjugated |
| Description | FIG4 Antibody (C-term) |
| Recommended Dilution | 1:1000 |
| Supplier | Abgent |
| Entrez Gene ID | 9896 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Isotype | IgG |
| Keywords | Primary Antibodies;Neuroscience;Signal Transduction |
| Notes | The protein encoded by this gene belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J. |
| Alias Names | Polyphosphoinositide phosphatase, 313-, Phosphatidylinositol 3,5-bisphosphate 5-phosphatase, SAC domain-containing protein 3, FIG4, KIAA0274, SAC3 |
| Product Type | Antibodies Primary |
| Research area | Neuroscience |
| Size | 80 µl |
| Source / Host | rabbit |
| Species Reactivity | human, mouse |
| Substrate / Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Technical Specifications | This FIG4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 846-874 amino acids from the C-terminal region of human FIG4. |
| Product Page Updated | 2023-11-23T14:38:54.086Z |
