Article No
AP19171c
Specifications
| MW | 47088 |
| NCBI Number | NP_004848.3 |
| Accession Number | P24588 |
| Application | WB |
| Article No | AP19171c |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | RB39500 |
| Clone Type | polyclonal |
| Conjugation | Unconjugated |
| Description | AKAP5 Antibody (Center) |
| Recommended Dilution | 1:1000 |
| Supplier | Abgent |
| Entrez Gene ID | 9495 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Isotype | IgG |
| Keywords | Primary Antibodies;Neuroscience;Signal Transduction |
| Notes | The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT. |
| Alias Names | A-kinase anchor protein 5, AKAP-5, A-kinase anchor protein 79 kDa, AKAP 79, H21, cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein, AKAP5, AKAP79 |
| Product Type | Antibodies Primary |
| Research area | Neuroscience |
| Size | 400 µl |
| Source / Host | rabbit |
| Species Reactivity | human |
| Substrate / Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Technical Specifications | This AKAP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-143 amino acids from the Central region of human AKAP5. |
| Product Page Updated | 2023-11-23T14:38:54.086Z |
