Article No
AP21019c-ev
Mouse Hes1 Antibody
Mouse Hes1 Antibody (C-term)
Antibodies Primary
Specifications
| MW | 29749 |
| Accession Number | P35428 |
| Application | WB |
| Article No | AP21019c-ev |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | RB51068 |
| Clone Type | polyclonal |
| Conjugation | Unconjugated |
| Description | Mouse Hes1 Antibody (C-term) |
| Recommended Dilution | 1:500 |
| Supplier | Abgent |
| Entrez Gene ID | 15205 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Isotype | IgG |
| Keywords | Primary Antibodies;Neuroscience |
| Notes | Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1 (By similarity). Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity. May play a role in a functional FA core complex response to DNA cross- link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage (By similarity). |
| Alias Names | Transcription factor HES-1, Hairy and enhancer of split 1, Hes1, Hes-1 |
| Product Type | Antibodies Primary |
| Research area | Neuroscience |
| Size | 80 µl |
| Source / Host | rabbit |
| Species Reactivity | mouse |
| Substrate / Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Technical Specifications | This Mouse Hes1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 205-239 amino acids from the C-terminal region of Mouse Hes1. |
| Product Page Updated | 2023-11-23T14:38:54.086Z |
