Article No
AP6269B-ev
Specifications
| MW | 22073 |
| NCBI Number | NP_004055.1 |
| Accession Number | P46527 |
| Application | WB, IF |
| Article No | AP6269B-ev |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | RB07333 |
| Clone Type | polyclonal |
| Conjugation | Unconjugated |
| Description | 27Kip1 Antibody (C-term) |
| Recommended Dilution | 1:10~50 |
| Supplier | Abgent |
| Entrez Gene ID | 1027 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Isotype | IgG |
| Keywords | Primary Antibodies;Cancer;Cell Biology |
| Notes | p27Kip1 is a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. |
| Alias Names | Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27, p27Kip1, CDKN1B, KIP1 |
| Product Type | Antibodies Primary |
| Size | 80 µl |
| Source / Host | rabbit |
| Species Reactivity | human |
| Substrate / Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Technical Specifications | This 27Kip1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 165-194 amino acids from the C-terminal region of human 27Kip1. |
| Product Page Updated | 2023-11-23T14:38:54.086Z |
