Article No
AP7072a
Specifications
| MW | 47504 |
| NCBI Number | NP_001093205.1;NP_001093206.1;NP_001816.2 |
| Accession Number | P17540 |
| Application | WB |
| Article No | AP7072a |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | RB5383/5384 |
| Clone Type | polyclonal |
| Conjugation | Unconjugated |
| Description | CKMT2 Antibody (N-term) |
| Recommended Dilution | 1:1000 |
| Supplier | Abgent |
| Entrez Gene ID | 1160 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Isotype | IgG |
| Keywords | Primary Antibodies;Metabolism;Signal Transduction |
| Notes | Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. |
| Alias Names | Creatine kinase S-type, mitochondrial, Basic-type mitochondrial creatine kinase, Mib-CK, Sarcomeric mitochondrial creatine kinase, S-MtCK, CKMT2 |
| Product Type | Antibodies Primary |
| Research area | Metabolism |
| Size | 400 µl |
| Source / Host | rabbit |
| Species Reactivity | human |
| Substrate / Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Technical Specifications | This CKMT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-86 amino acids from the N-terminal region of human CKMT2. |
| Product Page Updated | 2023-11-23T14:38:54.086Z |
