Article No
AP9473b-ev
MW | 41972 |
NCBI Number | NP_001005417.1;NP_003771.1;NP_085076.2 |
Accession Number | O60909 |
Application | WB |
Article No | AP9473b-ev |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
Clone | RB23048 |
Clone Type | polyclonal |
Conjugation | Unconjugated |
Description | B4GALT2 Antibody (C-term) |
Recommended Dilution | 1:1000 |
Supplier | Abgent |
Entrez Gene ID | 8704 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Isotype | IgG |
Keywords | Primary Antibodies;Metabolism;Signal Transduction |
Notes | B4GALT2 is one of type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme synthesizes N-acetyllactosamine in glycolipids and glycoproteins. Its substrate specificity is affected by alpha-lactalbumin but it is not expressed in lactating mammary tissue. |
Alias Names | Beta-1,4-galactosyltransferase 2, Beta-1,4-GalTase 2, Beta4Gal-T2, b4Gal-T2, 241-, UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 2, UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 2, Lactose synthase A protein, N-acetyllactosamine synthase, Nal synthase, Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase, Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase, 241-, B4GALT2 |
Product Type | Antibodies Primary |
Research area | Metabolism |
Size | 80 µl |
Source / Host | rabbit |
Species Reactivity | human, mouse |
Substrate / Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Technical Specifications | This B4GALT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-318 amino acids from the C-terminal region of human B4GALT2. |
Product Page Updated | 2023-11-23T14:38:54.086Z |