Article No
ARG54277-50
anti-CD45RA antibody [MEM-56] (APC)
anti-CD45RA antibody [MEM-56] (APC)
Antibodies Primary
Specifications
| NCBI Number | 5788 |
| Article No | ARG54277-50 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | MEM-56 |
| Clone Type | monoclonal |
| Conjugation | APC |
| Description | anti-CD45RA antibody [MEM-56] (APC) |
| Supplier | Arigo Biolaboratories Corporation |
| Immunogen | Human thymocytes and T lymphocytes. |
| Isotype | IgG2b |
| Notes | CD45 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012] |
| Alias Names | LY5; GP180; Receptor-type tyrosine-protein phosphatase C; CD45; L-CA; CD antigen CD45; Leukocyte common antigen; CD45R; LCA; T200; EC 3.1.3.48; B220 |
| Product Type | Antibodies Primary |
| Size | 50 tests |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C |
| Substrate / Buffer | PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA |
| Swiss-Prot No | P08575 |
| Product Page Updated | 2024-03-25T14:46:47.726Z |
