Article No
ASB-F9I67R-0.1
Mouse Anti-Chicken CD8α-CY5
Mouse Anti-Chicken CD8α-CY5
Antibodies Primary
Specifications
| NCBI Number | 403158, 100126556, 102085944 |
| Application | FC, IHC, ICC |
| Article No | ASB-F9I67R-0.1 |
| Biosite Brand | Biosite |
| Country Availability | all |
| Clone | CT-8 |
| Clone Type | monoclonal |
| Concentration | 0.1 mg/mL |
| Conjugation | Cy5 |
| Description | Mouse Anti-Chicken CD8α-CY5 |
| Supplier | Nordic Biosite |
| Format | Liquid |
| Immunogen | Chicken thymocytes and Ig-negative blood leukocytes |
| Isotype | IgG1 |
| Notes | In the chicken, the CD8 molecule is present in two forms - (i) a homodimer of two alpha chains and (ii) a heterodimer of an alpha chain and a beta chain. While the vast majority of CD8+ cells in the thymus, spleen, and blood of adult chickens express both CD8 alpha- and CD8 beta-chains, a relatively large proportion of the CD8+ TCR gamma/delta cells in the spleens of embryos and young chicks express only the alpha-chain of CD8. Among intestinal epithelial lymphocytes, the major CD8+ T cell populations present in mice are conserved but there is a population of TCR gamma/delta CD8 alpha/beta cells in the chicken that is not found in rodents. Chicken CD8 is expressed on approximately 80% of thymocytes, 15% of blood mononuclear cells, and 50% of spleen cells but less than 1% of cells in the bursa and bone marrow. The monoclonal antibody CT-8 recognizes the CD8 alpha chain and has been shown to react to a polymorphic determinant in turkey. |
| Previous Article No | ASB-I82G6T-0.1, ASB-822015, ASB-F9I67R-0.1 |
| Product Type | Antibodies Primary |
| Shipping Information | Ambient Temperature |
| Size | 0.1 mg |
| Source / Host | mouse |
| Species Reactivity | chicken |
| Storage | 2-8°C |
| Substrate / Buffer | Phosphate buffered saline containing < 0.1% sodium azide |
| Product Page Updated | 2024-01-11T10:51:07.446Z |
| Volume | 1.0 mL |
