Article No
ASB-L7V6M1-0.1
Rat Anti-Mouse CD11b-APC/CY7
Rat Anti-Mouse CD11b-APC/CY7
Antibodies Primary
Specifications
| NCBI Number | 16409 |
| Application | FC |
| Article No | ASB-L7V6M1-0.1 |
| Biosite Brand | Biosite |
| Country Availability | all |
| Clone | 3A33 |
| Clone Type | monoclonal |
| Concentration | 0.1 mg/mL |
| Conjugation | APC/Cy7 |
| Description | Rat Anti-Mouse CD11b-APC/CY7 |
| Supplier | Nordic Biosite |
| Format | Liquid |
| Immunogen | Peritoneal macrophages from B6D2 hybrid mice |
| Isotype | IgG2a |
| Notes | CD11b (integrin alphaM subunit) combines with CD18 (integrin beta2 subunit) to form the integrin Mac-1, also known as complement receptor 3 (CR3), which mediates adhesion to C3bi and ICAM-1 (CD54). Mac-1 is expressed at varying levels on granulocytes, macrophages, dendritic cells, NK cells, and B-1 cells in the peritoneal and pleural cavities. In addition to its role in binding C3bi on opsonized targets and mediation of the subsequent ingestion process, Mac-1 is important as an adhesion molecule in the transendothelial migration of monocytes and neutrophils. |
| Alias Names | Integrin αM, Mac-1α, Mac-1, Mo1, CR3, C3biR |
| Previous Article No | ASB-156019, ASB-L7V6M1-0.1 |
| Product Type | Antibodies Primary |
| Shipping Information | Ambient Temperature |
| Size | 0.1 mg |
| Source / Host | rat |
| Species Reactivity | mouse |
| Storage | 2-8°C |
| Substrate / Buffer | Phosphate buffered saline containing < 0.1% sodium azide and a stabilizer |
| Swiss-Prot No | P05555 |
| Product Page Updated | 2024-01-11T10:51:07.446Z |
| Volume | 1.0 mL |
