Article No
AT1117a
Accession Number | P05062 |
Application | ELISA |
Article No | AT1117a |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
Clone | 3B3 |
Clone Type | monoclonal |
Conjugation | Unconjugated |
Description | ALDOB Antibody |
Supplier | Abgent |
Entrez Gene ID | 229 |
Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
Isotype | IgG2a k |
Notes | Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance. |
Alias Names | Fructose-bisphosphate aldolase B, Liver-type aldolase, ALDOB, ALDB |
Product Type | Antibodies Primary |
Size | 100 µg |
Source / Host | mouse |
Species Reactivity | human |
Substrate / Buffer | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
Product Page Updated | 2023-11-23T13:40:12.472Z |