Article No
AT2603a
Specifications
| Accession Number | P56696 |
| Application | WB |
| Article No | AT2603a |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | 2H6 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | KCNQ4 Antibody |
| Recommended Dilution | 1:500~1000 |
| Supplier | Abgent |
| Entrez Gene ID | 9132 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Isotype | IgG3 k |
| Notes | The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene. |
| Alias Names | Potassium voltage-gated channel subfamily KQT member 4, KQT-like 4, Potassium channel subunit alpha KvLQT4, Voltage-gated potassium channel subunit Kv74, KCNQ4 |
| Product Type | Antibodies Primary |
| Protocol | 1:500~1000 |
| Size | 100 µg |
| Source / Host | mouse |
| Species Reactivity | human, mouse |
| Substrate / Buffer | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Product Page Updated | 2023-11-23T13:40:12.472Z |
