CD16/CD32

CD16/CD32

Article No BE0307-5MG
Product Type Antibodies Primary
Application FC, Block
Size 5mg

Specifications

Clone 2.4G2
Description InVivoMAb anti-mouse CD16/CD32
Supplier BioXcell
Immunogen BALB/c mouse macrophage cell line J774
Isotype IgG2b, k
Notes The 2.4G2 monoclonal antibody reacts specifically with mouse CD16 (FcγRIII) and CD32 (FcγRII). It has also been reported to react non-specifically via its Fc domain to FcγRI. CD16 and CD32 are expressed on B cells, monocytes/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. These receptors bind to the Fc portion of antibody-antigen complexes and play a role in adaptive immune responses. The 2.4G2 antibody is commonly used in flow cytometry staining experiments to prevent non-specific binding of IgG to the FcγIII and FcγII, and possibly FcγI, receptors prior to staining with antigen specific primary antibodies. The Fab fragments of the 2.4G2 antibody have also been used to block Fc receptors in vivo.
Purity >95%. Determined by SDS-PAGE
Source / Host rat
Storage Undiluted at 4°C in the dark
Substrate / Buffer PBS, pH 8.0. Contains no stabilizers or preservatives

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Shipping info

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Source/Host:

rat rat

Product insert: