Article No
BPS-60405
AP-1 Reporter - HEK293 Recombinant Cell Line (JNK signaling pathway)
AP-1 Reporter - HEK293 Recombinant Cell Line (JNK signaling pathway)
Cells
Specifications
| Additional Information | The stress-activated protein kinase/c-jun N-terminal kinase (SAPK/JNK) family of proteins incluces mitogen-activated protein kinases (MAPKs) that are activated by stress, inflammatory cytokines, mitogens, oncogenes, and inducers of cell differentiation and morphogenesis. Upon activation of the SAPK/JNK pathway, MAP Kinase Kinases phosphorylate and activate JNKs. The activated JNKs translocate to the nucleus where they phosphorylate and activate transcription factors such as c-Jun. cJun then binds to the activator protein-1 (AP1) response element and induces AP1 transcription. |
| Article No | BPS-60405 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Description | AP-1 Reporter - HEK293 Recombinant Cell Line (JNK signaling pathway) |
| Supplier | BPS Bioscience |
| Format | Aqueous solution containing DMSO |
| Notes | The AP-1 Reporter - HEK293 Cell Linee is designed for monitoring the activity of the JNK signaling pathway. The AP1 Reporter - HEK293 cell line contains a firefly luciferase gene under the control of AP1-responsive elements that are stably integrated into HEK293 cells. |
| Alias Names | JNK reporter, AP-1 cell line, activator protein-1 cell line |
| Product Type | Cells |
| Shipping Information | -80°C (dry ice) |
| Size | 2 vials |
| Source / Host | human |
| Storage | Store in liquid nitrogen immediately upon receipt. |
| Product Page Updated | 2024-05-03T09:13:48.379Z |
