Article No
BPS-79080
TPM3-TRKA Mutant, GST-Tag Recombinant
TPM3-TRKA Mutant, GST-Tag Recombinant
Proteins & Peptides
Specifications
| MW | 125 kDa |
| Accession Number | NM_002529 |
| Additional Information | TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family which is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. TRKA has a crucial role in the development and function of the nociceptive reception system as well as establishment of thermoregulation via sweating in humans. The oncogenic rearrangement of 5'-TPM3-3'-NTRK1 fusion gene has been found in papillary thyroid carcinomas. |
| Application | FA |
| Article No | BPS-79080 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Description | TPM3-TRKA Mutant, GST-Tag Recombinant |
| Supplier | BPS Bioscience |
| Format | Aqueous buffer solution |
| Notes | Human TPM3-TRKA fusion protein, TPM3 GenBank Accession No. NM_152263, a.a. 1-258, TRKA Genbank Accession No. NM_002529, a.a. 399-end, expressed in an E. coli expression system. TMP3-TRKA MW = 105 kDa. |
| Alias Names | TRKA, TPM3, TPM3 TRKA mutant, NTKR |
| Product Type | Proteins & Peptides |
| Research area | Neuroscience |
| Shipping Information | -80°C (dry ice) |
| Size | 10 µg |
| Species Reactivity | human |
| Storage | Store product at -80°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
| Substrate / Buffer | 50 mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
| Technical Specifications | Kinase Assay |
| UniProt Number | TRKA P04629; TPM3 P06753 |
| Product Page Updated | 2024-01-09T13:23:45.900Z |
