Antibodies Primary

MSH6

NEW
Anti-MSH6, rabbit monoclonal (BSR100) - Optibodies

Article No

BSH-3015-100

Application

IHC

Species Reactivity

human

Size

100 uL

Clone

BSR100

Source / Host

rabbit

Suggested protocols

Specifications

Application IHC
Article No BSH-3015-100
BioSite Brand Optibodies
Clone BSR100
Clone Type monoclonal
Description Anti-MSH6, rabbit monoclonal (BSR100) - Optibodies
Supplier Nordic BioSite
Format Concentrate
Notes Mismatch repair proteins are nuclear enzymes which participate in repair of mismatch errors during DNA replication. Loss of Mismatch repair proteins increases the number of DNA replication errors in the proliferating cells. Errors occur especially in areas of the genome with short repetitive nucleotide sequences - causing microsatellite instability (MSI). MSH6 is a mismatch repair protein which is not expressed in a high proportion of patients with MSI-H. MSH6 antibody can be useful for immunohistochemical analyses of MSH6 protein in neoplastic tissues and identification of loss of MSH6. Immunohistochemical analysis of MSH6 should be performed in IHC panel together with MLH1, MSH2 and PMS2.
Product Type Antibodies Primary
Protocol suitable for IHC
Size 100 uL
Source / Host rabbit
Species Reactivity human
Storage Store at 4℃
Substrate / Buffer TRIS with 0.03% sodium azide, pH7,2
Technical Specifications Control tissues: Tonsil, colon carcinoma with and without mutation
UniProt Number P52701
Product Page Updated 2019-06-04T07:34:23.706Z

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