Article No
BSH-4019-1
Application | IHC |
Article No | BSH-4019-1 |
Biosite Brand | Optibodies |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL, AF, AL, DZ, AS, AD, AO, AI, AQ, AG, AR, AM, AW, AU, AT, AZ, BS, BH, BD, BB, BY, BE, BZ, BJ, BM, BT, BO, BA, BW, BV, BR, IO, VG, BN, BG, BF, BI, KH, CM, CV, BQ, KY, CF, TD, CL, CN, CX, CC, CO, KM, CD, CG, CK, CR, HR, CU, CW, CY, CZ, DJ, DM, DO, TL, EC, EG, SV, GQ, ER, ET, FK, FJ, FR, GF, PF, TF, GA, GM, GE, DE, GH, GI, GR, GD, GP, GU, GT, GG, GN, GW, GY, HT, HM, HN, HK, HU, IN, ID, IR, IQ, IE, IM, IL, IT, CI, JM, JP, JE, JO, KZ, KE, KI, KW, KG, LA, LB, LS, LR, LY, LI, LU, MO, MK, MG, MW, MY, MV, ML, MT, MH, MQ, MR, MU, YT, MX, FM, MD, MC, MN, ME, MS, MA, MZ, MM, NA, NR, NP, NL, NC, NZ, NI, NE, NG, NU, NF, KP, MP, OM, PK, PW, PS, PA, PG, PY, PE, PH, PN, PL, PT, PR, QA, XK, RO, RW, RE, WS, SM, SA, SN, RS, SC, SL, SG, SX, SK, SI, SB, SO, ZA, GS, KR, SS, ES, LK, BL, SH, KN, LC, MF, PM, VC, SD, SR, SJ, SZ, CH, SY, ST, TW, TJ, TZ, TH, TG, TK, TO, TT, TN, TR, TM, TC, TV, UM, VI, UG, UA, AE, GB, US, UY, UZ, VU, VA, VE, VN, WF, EH, YE, ZM, ZW, AX |
Clone | BSR38 |
Clone Type | monoclonal |
Control Tissue | Tonsil, Colon |
Description | Anti-MUM1, rabbit monoclonal - Optibodies |
Recommended Dilution | IHC-P (1:100 - 1:400) |
Supplier | Nordic Biosite |
Format | Concentrate |
Notes | MUM1 is a nuclear transcriptional factor (IRF4 or Multiple Myeloma 1 ) and is expressed in final step of intragerminal center B cell differentiation and in post-germinal center B cells. MUM1 is usually mutually exclusive with BCL6 in nonneoplastic tissue. Nuclear expression is present also in a subpopulation of activated T- lymphocytes and expressed in normal and neoplastic melanocytes. In neoplasms MUM1 is found mainly in B-cell lymphoma and melanocytic lesions. In combination with CD138 and Ig´s makes MUM1 more specific marker for differentiating B-cells before plasma cell stage. MUM1 helps to divide diffuse large B cell lymphomas into germinal center (MUM1-) /non-germinal center (MUM1+) phenotypes and helps also to differentiate double hit from Burkitt and DLCL. |
Alias Names | IRF4 |
Product Type | Antibodies Primary |
Protocol | suitable for IHC-P |
Size | 1 ml |
Source / Host | rabbit |
Species Reactivity | human |
Storage | Store at 4℃ |
Substrate / Buffer | TRIS with 0.03% sodium azide, pH7,6 |
Technical Specifications | Control: Tonsil, Colon |
Product Page Updated | 2024-01-12T14:03:23.375Z |