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Decarestrictine D

Chemicals & Biochemicals

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Article No

BVT-0283-M001

Size

1 mg

Shipping Information

Article No

BVT-0283-M001

Size

1 mg

Specifications

CAS No	127393-89-9
MW	216.2
Article No	BVT-0283-M001
Country Availability	SE, FI, DK, NO, IS, EE, LV, LT
Description	Decarestrictine D
Supplier	Adipogen Life Sciences
Format	Powder
Notes	Chemical. CAS: 127393-89-9. Formula: C10H16O5. MW: 216.2. Isolated from Penicillium sp. Hypolipidemic. Cholesterol biosynthesis inhibitor.\|Hypolipidemic. Cholesterol biosynthesis inhibitor.
Molecular Formula	C10H16O5
Alias Names	Tuckolide; (4S,5S,8S,10R,E)-4,5,8-Trihydroxy-10-methyl-3,4,5,8,9,10-hexahydro-2H-oxecin-2-one
Product Type	Chemicals & Biochemicals
Purity	>98%
Research area	Metabolism
Shipping Information	RT
Size	1 mg
Solubility	Soluble in DMSO, methanol or acetone.
Stability	Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
Storage	-20°C, 4°C
Technical Specifications	Chemical. CAS: 127393-89-9. Formula: C10H16O5. MW: 216.2. Isolated from Penicillium sp. Hypolipidemic. Cholesterol biosynthesis inhibitor.
Product Page Updated	2024-02-01T08:25:01.492Z

Documentation

Datasheet

MSDS

References

Chemical investigation of the metabolites from the Canadian tuckahoe, Polyporustuberaster: W.A. Ayer, et al.; J. Nat. Prod. 55, 649 (1992) | Secondary metabolites by chemical screening. 8. Decarestrictines, a new family of inhibitors of cholesterol biosynthesis from Penicillium. I. Strain description, fermentation, isolation and properties: S. Grabley, et al.; J. Antibiot. (Tokyo) 45, 56 (1992) | Secondary metabolites by chemical screening. 9. Decarestrictines, a new family of inhibitors of cholesterol biosynthesis from Penicillium. II. Structure elucidation of the decarestrictines A to D: A. Göhrt, et al.; J. Antibiot. (Tokyo) 45, 66 (1992) | A non-enzymatic reaction in the late biosynthesis of the decarestrictine family: M. Mayer & R. Thiericke; J. Antibiot. (Tokyo) 46, 1372 (1993) | Synthesis of Tuckolide, a New Cholesterol Biosynthesis Inhibitor: M.B. Andrus & T.L. Shih; J. Org. Chem. 61, 8780 (1996) | An efficient total synthesis of decarestrictine D: P. Gupta, et al.; Eur. J. Org. Chem. 2008, 1195 (2008) | Asymmetric synthesis of allylsilanes by the borylation of lithiated carbamates: formal total synthesis of (-)-decarestrictine D: M. Binanzer, et al.; Angew. Chem. Int. Ed. 49, 4264 (2010)

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