Article No
CSB-RA153677A0HU-50
Application | ELISA, IHC |
Article No | CSB-RA153677A0HU-50 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
Clone | 10B10 |
Clone Type | monoclonal |
Conjugation | Unconjugated |
Description | CYP3A4 Recombinant Monoclonal Antibody |
Recommended Dilution | IHC 1:50-1:200 |
Supplier | Cusabio |
Entrez Gene ID | 1576 |
Gene Symbol | CYP3A4 |
Immunogen | A synthesized peptide derived from human Cytochrome P450 3A4 |
Isotype | IgG |
Notes | Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,8-cineole 2-exo-monooxygenase. The enzyme also hydroxylates etoposide (PubMed:11159812). Catalyzes 4-beta-hydroxylation of cholesterol. May catalyze 25-hydroxylation of cholesterol in vitro (PubMed:21576599). |
Product Type | Antibodies Primary |
Purification | Affinity Purified |
Shipping Information | BLUE ICE |
Size | 50ul |
Source / Host | rabbit |
Species Reactivity | human |
Storage | -80°C |
UniProt Number | P08684 |
Product Page Updated | 2024-01-24T14:15:14.857Z |