14-3-3 Epsilon
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Specifications
| MW | Recombinant human 14-3-3 Epsilon demonstrates approximately 54 kDa band by SDS-PAGE analysis. |
| Country Availability | DK, EE, FI, FO, GL, IS, LT, LV, NO, SE |
| Concentration | 1.72 μg/μl |
| Data Sheet Link | https://www.mblintl.com/assets/cy-r2142.pdf |
| Description | 14-3-3 ε (Human) |
| Supplier | MBL International Corp. |
| CE/IVD | false |
| Notes | 14-3-3 protein family is highly conserved from plants to mammals and ubiquitously expressed cellular proteins. In mammals, there are seven isoforms encoded by a distinct gene (Beta, Epsilon, Gamma, Sigma, Eta, Tau and Zeta). More than 200 target proteins of the 14-3-3 protein family have been identified. Interactions of 14-3-3 proteins and the target proteins are dependent on phosphorylation of serine/threonine residue on the target proteins with some exceptions. 14-3-3 is deeply and widely involved in mitogenic signaling, cell cycle regulation and cell death/survival, suggesting the family plays important role in human neoplastic and neurological diseases. |
| Alias Names | The gene accession number is U43430. |
| References | 1. Mackintosh C. Dynamic interactions between 14-3-3 proteins and phosphoproteins regulate diverse cellular processes. Biochem J. 2004 Jul 15;381(Pt 2):329-42. 2. Dougherty MK, Morrison DK. Unlocking the code of 14-3-3. J Cell Sci. 2004 Apr 15;117(Pt 10):1875-84. 3. Hermeking H. The 14-3-3 cancer connection. Nat Rev Cancer. 2003 Dec;3(12):931-43. 4. Berg D, Holzmann C, Riess O. 14-3-3 proteins in the nervous system. Nat Rev Neurosci. 2003 Sep;4(9):752-62. |
| Storage | -70°C |
| Substrate / Buffer | Recombinant human 14-3-3 Epsilon is supplied frozen in phosphate buffered saline (PBS) containing 50 % glycerol. |
| Product Page Updated | 2019-01-15T09:09:13.918Z |
Shipping info
The delivery time for this item is approximately 8-12 business days. If other deviations occur, this will be noted on the order confirmation or communicated via email. Please note, we do reserve the right to select the best packaging and shipping method in order to insure the stability of the product and allow efficient order tracking.
Product insert:
Datasheet