Antibodies Primary

AAnti-CD11c (Mouse) mAb-PE

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AAnti-CD11c (Mouse) mAb-PE

Article No

FP20106002

Application

FC

Species Reactivity

mouse

Size

25 µg

Clone

N418

Source / Host

hamster

Shipping Information

4°C

Product insert

Specifications

Application FC
Article No FP20106002
Country Availability SE, FI, DK, NO, IS, EE, LV, LT, FO, GL, RU
Clone N418
Clone Type monoclonal
Concentration 0.2 mg/mL
Conjugation PE
Description AAnti-CD11c (Mouse) mAb-PE
Supplier MBL International Corp.
Isotype IgG
Notes The N418 monoclonal antibody specifically reacts with the integrin αx chain of the mouse CD11c, which is expressed on dendritic cells, CD4-/CD8+ intestinal intraepithelial lymphocytes (IEL) and some activated T lymphocytes. Low levels of CD11c were detected on mouse splenic natural killer cells and on the monocyte/macrophage lineage cells.CD11c expression is upregulated on IEL and T lymphocytes after activation. It binds to CD54, fibrinogen and iC3b and influences the leukocyte adhesive interactions. The N418 antibody binds to CD11c on splenic dendritic cells of the mouse in the T-dependent areas. It also contributes to the binding of iC3b.
Product Type Antibodies Primary
References Kaneko, Y., et al., Eur J Immunol. 26, 3061-3065 (1996) Ferlin, W. G., et al., Eur J Immunol. 26, 2911-2915 (1996) Kashiwada, M., et al., Eur J Immunol. 26, 1451-1458 (1996)
Shipping Information 4°C
Size 25 µg
Source / Host hamster
Species Reactivity mouse
Storage 4°C
Substrate / Buffer Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Technical Specifications The N418 monoclonal antibody specifically reacts with the integrin αx chain of the mouse CD11c, which is expressed on dendritic cells, CD4-/CD8+ intestinal intraepithelial lymphocytes (IEL) and some activated T lymphocytes. Low levels of CD11c were detected on mouse splenic natural killer cells and on the monocyte/macrophage lineage cells.CD11c expression is upregulated on IEL and T lymphocytes after activation. It binds to CD54, fibrinogen and iC3b and influences the leukocyte adhesive interactions. The N418 antibody binds to CD11c on splenic dendritic cells of the mouse in the T-dependent areas. It also contributes to the binding of iC3b.
Product Page Updated 2020-06-10T09:56:05.519Z

Shipping info

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