Article No
GTX13826
Specifications
| Application | FC, ICC, IF, IHC, MS, WB |
| Article No | GTX13826 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 401.8B11.3D9 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | RPE65 antibody [401.8B11.3D9] |
| Supplier | GeneTex |
| Entrez Gene ID | 282043 |
| Gene Symbol | RPE65 |
| Immunogen | Bovine RPE65 microsomal membrane proteins. [UniProt# Q28175] |
| Isotype | IgG1 |
| Notes | Plays important roles in the production of 11-cis retinal and in visual pigment regeneration. The soluble form binds vitamin A (all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester. The membrane form, palmitoylated by LRAT, binds all-trans-retinyl esters, making them available for IMH (isomerohydrolase) processing to all-cis-retinol. The soluble form is regenerated by transferring its palmitoyl groups onto 11-cis-retinol, a reaction catalyzed by LRAT. The enzymatic activity is linearly dependent of the expression levels and membrane association. |
| Product Type | Antibodies Primary |
| Protocol | WB: 1:500 - 1:1000. ICC/IF: 1:10 - 1:500. IHC-P: 1:250 - 1:500. IHC-Fr: 1:250. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications. |
| Purification | Protein G Purified |
| Size | 100µl |
| Source / Host | mouse |
| Species Reactivity | chicken, cow/bovine, dog/canine, frog, human, mouse, pig/porcine, rat |
| Storage | 4°C, -80°C |
| UniProt Number | Q28175 |
| Product Page Updated | 2024-01-03T10:31:47.950Z |
