Article No
GTX18177
Insulin Receptor
Insulin Receptor antibody [1.B.109]
Antibodies Primary
Specifications
| Application | IP |
| Article No | GTX18177 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 1.B.109 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | Insulin Receptor antibody [1.B.109] |
| Supplier | GeneTex |
| Entrez Gene ID | 3643 |
| Gene Symbol | INSR |
| Immunogen | Purified human alpha subunit of insulin receptor. |
| Isotype | IgG2a |
| Notes | This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015] |
| Product Type | Antibodies Primary |
| Purification | Protein G Purified |
| Size | 25µg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C, -80°C |
| UniProt Number | P06213 |
| Product Page Updated | 2024-01-03T10:31:47.950Z |
